I would strongly recommend against doing anything as drastic as that. These attacks are usually short lived and you can find your inbox again by writing a pretty simple filter that looks for NDR wording and tossing those messages into a folder for a short term solution.
For a long term solution, if you do not already have a managed perimeter defense around your mail server, it is time to look at getting one. We offer services from many different vendors and our own in house solution as well. If you have any more questions, please give us a call or send a message to sales@mxtoolbox.com to see what is available.
Peter
Peter
Product Development Engineer
peter@MXToolBox.com
512-637-8762